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pentobarbital will lessen the level or outcome of tamoxifen by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Monitor.pentobarbital will reduce the extent or effect of conivaptan by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital decreases levels of vandetanib by impacting hepatic/intestinal enzym